In 1998 Dimitri Van De Ville obtained a masters in computing from the University of Ghent, Belgium, followed in 2002 with a doctorate. Between 2002 and 2005 he worked towards a postdoctorate in the Biomedical Imaging Group at EPFL and in 2005 took responsibility for the signal processing unit of the Faculty of Medicine of the University of Geneva and the HUG. This unit is part of the Biomedical Imaging Center (GBIF), a joint initiative to Lake Geneva institutions in the field of medical imaging. In 2009, he obtained a professorship of NSF and joined as assistant professor in the Department of Radiology and Medical Informatics of the Faculty of Medicine of the University of Geneva and bioengineering Interfaculty Institute of the EPFL. He was appointed associate professor at both institutions in September 2015.

As part of his research, he has developed innovative tools neuroimaging, either for the acquisition, analysis or interpretation of data. Based on network models and dynamical systems, and it is to better understand brain function and to provide new markers of cognitive and clinical conditions.